chloropropamide chemical properties
iupac name: chloropropamide
the mf of chlorpropamide (cas no.94-20-2) is c10h13cln2o3s.
the mw of chlorpropamide (cas no.94-20-2) is 276.74.
synonyms of chlorpropamide (cas no.94-20-2): 1-(4-chlorophenyl)sulfonyl-3-propyl-urea ; 4-chlor-n-(propylcarbamoyl)benzolsulfonamid ; benzenesulfonamide, 4-chloro-n-((propylamino)carbonyl)- ; oradian
appearance: white crystalline powder
stability: stable. combustible
index of refraction: 1.552
density: 1.334 g/ml
melting point: 128 °c
chlorpropamide (cas no.94-20-2) is sulfonylurea oral hypoglycemic agents which mainly selectively act on the pancreatic islet-β-cells, promoting insulin secretion.chlorpropamide has a relatively large side-effects, so the using of the drug are decreasing trend.
chlorobenzene sulfonamide reacts with chlorobenzene sulfonyl amide,generating c urea sodium salt. then hydrochloric acid, refined to derive. another method is based on chlorobenzene sulfonamide, isopropyl isocyanate, triethylamine as raw materials